Murder on the Orient Express retains the main plot elements of Agatha Christie's novel of the same name. She is aided by famous detective Hercule Poirot. The plot follows an amateur sleuth, Antoinette Marceau, and her investigation of a murder with twelve possible suspects aboard the Orient Express, which has been blocked by an avalanche in the Kingdom of Yugoslavia during 1934. The setting is five years before the events in Agatha Christie: And Then There Were None, with a largely unrelated storyline. Agatha Christie: Murder on the Orient Express is a 2006 point-and-click third-person adventure game developed by AWE Productions and published by The Adventure Company for Microsoft Windows. The game is the second installment in The Adventure Company's Agatha Christie series.